“There was no evidence of adverse cognitive effects, including incidence of dementia, deterioration in global cognition, or specific cognitive domains associated with statin use in individuals aged ≥60 years. A systematic review published in the Journal of Clinical Lipidology (Jan-Feb. The reports are generally nonserious, and reversible upon statin discontinuation, with variable times to symptom onset (1 day to years) and symptom resolution (median of 3 weeks).” Study Rejects Idea that Statins Cause Transient Global Amnesia:Įven with the statement in the FDA-approved prescribing information, many doctors doubt that statins cause transient global amnesia. These cognitive issues have been reported for all statins. “There have been rare postmarketing reports of cognitive impairment (e.g., memory loss, forgetfulness, amnesia, memory impairment, confusion) associated with statin use. The FDA does require this advisory in the prescribing information: There has been surprisingly little research into this possible adverse reaction. We also have heard from dozens of other readers who attribute their TGA events to statin use.
He wrote a book about his experience: Lipitor: Thief of Memory. Graveline believed statins cause transient global amnesia. Do Statins Cause Transient Global Amnesia?ĭr. I could not have doctored a mouse and knew nothing of marriage.
#Drugs that cause temporary amnesia full
“The following year my episode of transient global amnesia lasted for 12 hours, during which time I was a 13-year-old high school student with full recall for that particular day as to assignments, teachers, books, classmates, etc., but laughed hysterically when they told me I was married with children and a family doctor. Eight weeks later he had another TGA event: His doctors convinced him that he needed to go back on Lipitor. Graveline went in for his NASA physical (he was a former physician astronaut). The neurologist said, however, that statins do not cause transient global amnesia (TGA).”Ī year later Dr. As a family doctor with 23 years of experience, the first thing I thought about as a cause was the new medicine I was on. I was naturally amazed and quite anxious. I came to my senses in the emergency room listening to my wife tell me how her day and mine had gone. I did not know my new wife (although we had been together 6 years), neither did I know my new home. “In my first episode the amnesia lasted for 6 hours with retrograde loss for some 10 years into the past.
It is usually associated with retrograde loss of memory for months, years or decades into your past. “Transient global amnesia is the abrupt onset, within seconds, of the complete inability to formulate new memories. Graveline stated statins cause Transient Global Amnesia: Graveline shared his story on our website at this link. His description was quite similar to yours. He had been taking atorvastatin (Lipitor) prior to each “attack.” Duane Graveline wrote to us about his personal experience with two episodes of transient global amnesia (TGA). I was then and am still taking 20 mg atorvastatin daily.Ī. I have not experienced transient global amnesia since. All was normal, and my memory came back perfectly after about six hours.
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I couldn’t remember his phone number either, but I did know how to look it up.Įmergency room personnel gave me a battery of tests and admitted me. I called a friend to take me to the hospital, thinking that I was having a stroke. In fact, I didn’t even know my home phone number. To my surprise, I couldn’t remember them. While I lathered up, I started reviewing my day’s upcoming activities, as I usually do. A few years ago, I awoke and jumped in the shower. Could Statins Cause Transient Global Amnesia? One reader shared this scary experience: Definitely not real! Some doctors have suggested that patient advocates or health professionals who discuss statin side effects are guilty of fear mongering ( JAMA Cardiology, June 26, 2019). That is to say, they are all in your head: imaginary.
Patient-reported adverse reactions are often attributed to psychosomatic complaints. There are reports in the medical literature that suggest statins barely cause any side effects ( European Journal of Preventive Cardiology, March 12, 2014). The issue of statin side effects makes a lot of health care professionals uneasy. Let’s not forget simvastatin ( Zocor), rosuvastatin ( Crestor), pravastatin ( Pravachol), pitavastatin ( Livalo), fluvastatin ( Lescol) and lovastatin ( Mevacor). Atorvastatin ( Lipitor) is the number one most prescribed drug in the country. For example, do statins cause transient global amnesia or other cognitive challenges? Are Statin Side Effects All in Your Head?Īt last count, 45 million people in the US take statins daily. Questions about side effects create confusion. Most physicians insist they protect the heart. Statin-type cholesterol-lowering drugs have been on the market for more than 30 years.
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